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[] The administration of NAC (1 g/day for a week and then 2.4 g/day for 9 weeks) in addition to SSRI citalopram significantly reduced OCD symptoms in 34 paediatric and adolescent outpatients (age: 1021 years) with OCD in a 10-week multicentre randomized, double-blind placebo-controlled trial, even though the effects of NAC on SSRI-resistant OCD are unclear

Effects on cardiovascular morbidity and mortality In total, 33, 37 and seven RCTs reported information on (externally adjudicated) major adverse cardiovascular events (MACE), cardiovascular mortality and hospitalization due to heart failure (HHF), respectively (Supplementary Figs